Research In Practice Blog
The Research In Practice Blog shares credible and timely commentary on the latest news, research and events in clinical effectiveness. Catch up on our most recent posts below. Check back often for updates!
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Children frequently experience sleep issues, which affect their health and learning. Research behind this study developed and tested a Pediatric Primary Care Sleep Screener tool which significantly improved the identification and management of sleep disorders in children.
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IgE-mediated food allergy is the most common cause of anaphylaxis in children, with peanut being a common culprit food. There has been much interest in food allergy prevention following the landmark LEAP study in 2015. In this study, prevention of peanut allergy was observed when peanuts were introduced early to infants with the risk factors atopic dermatitis (or eczema) or egg allergy.
Following the LEAP study, multi-organization consensus guidelines were published, starting with initial early peanut introduction guidelines in 2015, then addendum guidelines in 2017, followed by more recent…
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Antibiotic administration for suspected late-onset infection is common among preterm infants, but most are ultimately found to be uninfected. Antibiotic stewardship efforts are limited by the lack of large-scale data describing contemporary patterns of late antibiotic use among this population.
While considerable attention has been given to neonatal antibiotic stewardship to mitigate the risk of early-onset sepsis, stewardship for late antibiotic use is hindered by the lack of consensus recommendations to guide empiric antibiotic selection, partly due to the low quality of evidence and to…
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A new study published in Pediatrics investigates how researchers from Children’s Hospital of Philadelphia and Clinical Futures have successfully and effectively scaled dental varnish application across the primary care network using iterative quality improvement (QI), electronic health record (EHR) design, and change management strategies.
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Researchers developed and measured computable phenotype or algorithm that can identify pulmonary embolism in children across a data set.
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A new study, published in JAMA Network Open, conducted by researchers at the Children’s Hospital of Philadelphia (CHOP), along with several academic partners, evaluated the effectiveness of stone clearance and patient-reported outcomes in children and adolescents who underwent either ureteroscopy or shockwave lithotripsy. This research is part of the Pediatric KIDney Stone (PKIDS) trial, which is the largest comparative effectiveness study of surgical interventions for children and adolescents with kidney stones. CHOP founded the PKIDS Care Improvement Network in 2019, which now includes 31…
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Achieving lung aeration is the most critical task for preterm neonates during the transition to life outside the womb. Nearly all extremely preterm neonates require help breathing after birth through continuous positive airway pressure (CPAP) or positive pressure ventilation (PPV). Researchers from the University of Pennsylvania and Children’s Hospital of Philadelphia (CHOP), including lead investigators Elizabeth Foglia, MD, MSCE and Clinical Futures’ fellow, David Rub, MD, aimed to investigate which respiratory targets are associated with successful lung aeration in preterm infants…
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The goal of this study was to gather data on factors that contributed to past infant-feeding decisions for PLHIV and factors they would consider in a context more accepting of breastfeeding while living with HIV.
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A recent study by researchers from Clinical Futures titled, “Disparities in Nirsevimab Uptake Across a Pediatric Primary Care Network,” aims to explore nirsevimab distribution among infants born across a large Pediatric Primary Care Network to determine factors associated with nirsevimab receipt.
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In a new Research Brief in Hospital Pediatrics, a team of researchers from Clinical Futures, including Aditi Vasan, MD, MSHP, Chén Kenyon, MD, MSHP, Chris Feudtner, MD, PhD, MPH, and Alexander Fiks, MD, MSCE, aimed to explore the prevalence of social needs reported by caregivers of hospitalized children with CCCs. Their findings support the development of new screening and support programs.
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In this video, part of our Clinical Conversations Series, Brian Jenssen, MD, MSHP, an expert from Clinical Futures, provides a comprehensive overview of his recent research on youth tobacco use.
