Dr. Mukhopadhyay’s overall research goal is to understand effects of early-life factors on childhood outcomes. Her work has focused on the role of neonatal infections and antimicrobial therapy in altering early colonization with subsequent impact on health outcomes. Her work on epidemiology of neonatal infectious disease and early life antibiotic exposure with childhood atopy and obesity is funded by the National Institutes of Health (NICHD) and the Centers of Disease Control and Prevention. She has also received funding as part of the Physician Scientist Award from the Society of Pediatric Research and the Transdisciplinary Awards Program in Translational Medicine and Therapeutics from the University of Pennsylvania to determine differences in microbiome development trajectories in preterm infants based on early-life factors. She has led the recruitment of longitudinal birth cohorts in both healthy term and preterm population and created a repository of biospecimens and clinical databases. The ultimate aim of Dr. Mukhopadhyay’s work is to use the translational and epidemiological knowledge gained from these cohorts to drive targeted change in early life care that will promote better health outcomes for children throughout their lifespan.