TitleFDG-PET in two cases of neurofibromatosis type 1 and atypical malignancies.
Year of Publication2014
AuthorNumber of Pagese345-8
Date Published2014 Apr
ISSN Number1198-0052
Abstract<p>Patients with neurofibromatosis type 1 (nf1) are at increased risk for both benign and malignant tumours, and distinguishing the malignant potential of an individual tumour is a common clinical problem in these patients. Here, we review two cases of uncommon malignancies (Hodgkin lymphoma and mediastinal germ-cell tumour) in patients with nf1. Although (18)F-fluorodeoxyglucose positron-emission tomography (fdg-pet) has been used to differentiate benign neurofibromas from malignant peripheral nerve sheath tumours, fdg-pet characteristics for more rare tumours have been poorly described in children with nf1. Here, we report the role of pet imaging in clinical decision-making in each case. In nf1, fdg-pet might be useful in the clinical management of unusual tumour presentations and might help to provide information about the malignant potential of uncommon tumours.</p> DOI10.3747/co.21.1803
Alternate TitleCurr Oncol
PMID24764718
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