Title

Complications preceding early deaths in Black and White children with acute myeloid leukemia.

Year of Publication

2017

Date Published

2017 Jul 20

ISSN Number

1545-5017

Abstract

<p>Black patients have a twofold increased risk of induction mortality compared to White patients with acute myeloid leukemia (AML). We reviewed diagnosis and billing data from Pediatric Health Information System for 28 AML Induction I deaths to investigate conditions preceding death in White and Black patients. Half of deaths occurred within 10 days of initial diagnostic admission. Respiratory, cardiac, renal, and infectious complications were common prior to both White and Black deaths. Deaths in White patients were more commonly preceded by intracranial hemorrhage compared to deaths in Black patients. Future studies should assess management approaches of complications by race to identify modifiable processes that reduce mortality.</p>

DOI

10.1002/pbc.26712

Alternate Title

Pediatr Blood Cancer

PMID

28727288

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