Title

Bortezomib Inpatient Prescribing Practices in Free-Standing Children's Hospitals in the United States.

Year of Publication

2016

Number of Pages

e0151362

Date Published

2016

ISSN Number

1932-6203

Abstract

<p>This study is a pharmacoepidemiologic description of pediatric bortezomib use. Exposure was identified through billing codes in patients admitted to US children's hospitals that participated with the Pediatric Health Information System between 2004 and 2013. Associated information on underlying diseases, demographics, institutional use, mortality, and physician type was collected. Exposure to bortezomib was identified in 314 patients. Hematologist/Oncologists prescribed half of the bortezomib used. Use increased during the study period. Inpatient volume was positively correlated with bortezomib utilization. Bortezomib use in pediatrics is increasing for a variety of diseases. Variation in use exists across institutions. Further studies are needed to characterize bortezomib's efficacy in pediatric diseases.</p>

DOI

10.1371/journal.pone.0151362

Alternate Title

PLoS ONE

PMID

26978062

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