Title

Acute Kidney Injury and Pediatric Bone Health.

Year of Publication

2020

Number of Pages

635628

Date Published

2020

ISSN Number

2296-2360

Abstract

<p>Acute kidney injury (AKI) has been associated with deleterious impacts on a variety of body systems. While AKI is often accompanied by dysregulation of mineral metabolism-including alterations in calcium, phosphate, vitamin D, parathyroid hormone, fibroblast growth factor 23, and klotho-its direct effects on the skeletal system of children and adolescents remain largely unexplored. In this review, the pathophysiology of dysregulated mineral metabolism in AKI and its potential effects on skeletal health are discussed, including data associating AKI with fracture risk.</p>

DOI

10.3389/fped.2020.635628

Alternate Title

Front Pediatr

PMID

33634055

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