Title
Successful treatment of pulmonary mucormycosis in two pediatric hematopoietic stem cell transplant patients.
Year of Publication
2018
Number of Pages
e13270
Date Published
2018 Nov
ISSN Number
1399-3046
Abstract
<p>Pulmonary mucormycosis diagnosed immediately after hematopoietic stem cell transplantation frequently portends a poor prognosis. However, here we describe two cases in children that were treated successfully to highlight the efficacy of a multidisciplinary approach. Despite diagnosis in the immediate post-transplant period and requirement for ongoing immunosuppression to prevent or treat GVHD, both are long-term survivors due to early surgical debridement with transfusion support and prompt initiation of targeted antifungal therapy. In the absence of evidence-based treatment guidelines, survival of pulmonary mucormycosis is achievable even in high-risk patients with a multidisciplinary team to guide management.</p>
DOI
10.1111/petr.13270
Alternate Title
Pediatr Transplant
PMID
30014584