First name
Maria
Middle name
M
Last name
Gramatges

Title

Child and family perceptions of satisfaction with neutropenia management in pediatric acute myeloid leukemia.

Year of Publication

2023

Number of Pages

e30420

Date Published

05/2023

ISSN Number

1545-5017

Abstract

PURPOSE: Chemotherapy for pediatric acute myeloid leukemia (AML) is very intensive and many, but not all centers, require extended hospitalization until neutrophil recovery. Child and family preferences, beliefs, and experiences around hospitalization have not been systematically assessed.

PATIENTS AND METHODS: We recruited children with AML and their parents from nine pediatric cancer centers across the United States for a qualitative interview about their experiences of neutropenia management. Interviews were analyzed using a conventional content analysis approach.

RESULTS: Of 116 eligible individuals, 86 (74.1%) agreed to participate. Interviews were conducted with 32 children and 54 parents from 57 families. Of these 57 families, 39 were cared for as inpatients and 18 were managed as outpatients. A very high proportion of respondents in both groups reported satisfaction with the discharge management strategy recommended by the treating institution: 86% (57 individuals) of respondents who experienced inpatient management and 85% (17 individuals) of respondents who experienced outpatient management expressed satisfaction. Respondent perceptions associated with satisfaction related to safety (access to emergency interventions, infection risk, close monitoring) and psychosocial concerns (family separation, low morale, social support). Respondents believed it could not be assumed that all children would have the same experience due to varied life circumstances.

CONCLUSION: Children with AML and their parents express a very high degree of satisfaction with the discharge strategy recommended by their treating institution. Respondents saw a nuanced tradeoff between patient safety and psychosocial concerns that was mediated by a child's life circumstances.

DOI

10.1002/pbc.30420

Alternate Title

Pediatr Blood Cancer

PMID

37194639
Inner Banner
Publication Image
Featured Publication
No
Inner Banner
Publication Image

Title

A report from the Leukemia Electronic Abstraction of Records Network on risk of hepatotoxicity during pediatric acute lymphoblastic leukemia treatment.

Year of Publication

2022

Number of Pages

Date Published

2022 Jan 27

ISSN Number

1592-8721

Abstract

<p>Not available.</p>

DOI

10.3324/haematol.2021.279805

Alternate Title

Haematologica

PMID

35081687
Inner Banner
Publication Image
Inner Banner
Publication Image

Title

Identifying patient- and family-centered outcomes relevant to inpatient versus at-home management of neutropenia in children with acute myeloid leukemia.

Year of Publication

2018

Number of Pages

Date Published

2018 Apr

ISSN Number

1545-5017

Abstract

<p>Efficacy of therapeutic strategies relative to patient- and family-centered outcomes in pediatric oncology must be assessed. We sought to identify outcomes important to children with acute myeloid leukemia and their families related to inpatient versus at-home management of neutropenia. We conducted qualitative interviews with 32 children ≥8&nbsp;years old and 54 parents. Analysis revealed the impact of neutropenia management strategy on siblings, parent anxiety, and child sleep quality as being outcomes of concern across respondents. These themes were used to inform the design of a questionnaire that is currently being used in a prospective, multiinstitutional comparative effectiveness trial.</p>

DOI

10.1002/pbc.26927

Alternate Title

Pediatr Blood Cancer

PMID

29286570
Inner Banner
Publication Image
Inner Banner
Publication Image