First name
Christopher
Middle name
C
Last name
Blyth

Title

Weighing the Risks of Perimyocarditis With the Benefits of SARS-CoV-2 mRNA Vaccination in Adolescents.

Year of Publication

2021

Date Published

2021 Jul 16

ISSN Number

2048-7207

DOI

10.1093/jpids/piab061

Alternate Title

J Pediatric Infect Dis Soc

PMID

34270752

Title

Macrolides in Children With Community-Acquired Pneumonia: Panacea or Placebo?

Year of Publication

2018

Number of Pages

71-7

Date Published

2018 Feb 19

ISSN Number

2048-7207

Abstract

<p>Pneumonia, most often caused by a respiratory virus, is common in childhood. Mycoplasma pneumoniae also is detected frequently, particularly in older children in the era of pneumococcal conjugate vaccination. Despite recommendations for β-lactam antibiotics, macrolide antibiotics, including erythromycin, clarithromycin, and azithromycin, are prescribed frequently to children with acute lower respiratory infection. However, the significance of detecting "atypical" pathogens, including M pneumoniae, in children remains contentious. Considering the potential for antibacterial and anti-inflammatory activities of macrolides, our understanding of the role of these drugs in acute and chronic infections and in inflammatory conditions is changing. Some observational data have revealed improved outcomes in adults and children with pneumonia who are prescribed macrolides, although its widespread use has led to increases in macrolide resistance in Streptococcus pneumoniae and M pneumoniae. Clinical trials to define the role of macrolides in pediatric acute respiratory infection must be prioritized.</p>

DOI

10.1093/jpids/pix083

Alternate Title

J Pediatric Infect Dis Soc

PMID

29096010

WATCH THIS PAGE

Subscription is not available for this page.