<p>Administrative and surveillance data are used frequently in healthcare epidemiology and antimicrobial stewardship (HE&amp;AS) research because of their wide availability and efficiency. However, data quality issues exist, requiring careful consideration and potential validation of data. This methods paper presents key considerations for using administrative and surveillance data in HE&amp;AS, including types of data available and potential use, data limitations, and the importance of validation. After discussing these issues, we review examples of HE&amp;AS research using administrative data with a focus on scenarios when their use may be advantageous. A checklist is provided to help aid study development in HE&amp;AS using administrative data. Infect Control Hosp Epidemiol 2016;1-10.</p>